Space Marines are entirely artificial, so nothing that makes them 'space marine', would come out of their DNA, which is basically just human. Tons more hormones, but that's about it.
Insertion of the space marine organs though does have an effect on applicants, as the geneseed of the organs will change them, but it's something which only comes from the applicant going through the transformation progress.
For your case, the Space Wolves could turn their crew into space marines. Doesn't really matter where the crew came from, as once they are space marines, the space wolf geneseed will effect them, it's not that they are from Fenris that this is the case.
Keep in mind, that the application progress is extreamly difficult, and only applications of extreame physical and mental strength will have a chance to survive.
Basically, as long as they are using Space Wolf geneseed to make their space marine organs and such, they are a space wolf successor, so you're good to go.