This is a thought that just occurred to me. Space Marines use equipment that long predates their creation right? The Land Speeder, Raider, Rhino etc existed long before they came along right, along with their bikes no doubt as well. And these bikes are way too big for a normal human to ride, and the Speeder is said to be far too maneuverable for a normal human to use to its full potential, right? Well then, who were they originally built for?
Now a dull answer might be that they were still made for ordinary humans (maybe the Mechanicus scaled the bikes up), but I think that a more interesting answer, even if it's total bullamphetamine parrot, is that these machines were originally built to be used by the Iron Men. That I think would be very cool indeed. Some of the machines used today by humanity's ultimate defenders were once used against them by one of their biggest threats.